A New Microtubule Gliding Assay Analysis of Microtubule Persistence Length
نویسندگان
چکیده
منابع مشابه
Selective control of gliding microtubule populations.
First lab-on-chip devices based on active transport by biomolecular motors have been demonstrated for basic detection and sorting applications. However, to fully employ the advantages of such hybrid nanotechnology, versatile spatial and temporal control mechanisms are required. Using a thermo-responsive polymer, we demonstrate the selective starting and stopping of modified microtubules gliding...
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Microtubules and actin fibres are dynamic fibres constituting the cell skeleton. They show seemingly computational behaviours. Indeed, depending on conditions of reaction, they self-organise into temporal and/or spatial morphologies in vitro and act as micro-machine processors and actuators in living cells. I discuss here about their possible reuse to construct microtubule-based computational s...
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The mechanics of microtubules, cylindrical protein filaments that constitute the cytoskeleton, have been well characterized on long length scales. Here, we investigate the persistence length of short (approximately 0.1 microm) ends of microtubules by measuring the trajectories of kinesin-propelled microtubules under perpendicular electric forces. We relate the measured trajectory curvatures to ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2011
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.2653